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John P. Klein, PhD Professor and Head Division of Biostatistics Medical College of Wisconsin Education |
Professor Klein joined the Division of Biostatistics in the summer of 1993 coming from the Ohio State University where he was Professor of Statistics and Preventive Medicine. He was formerly the Statistical Director of the Ohio State University Comprehensive Cancer Center. He is an elected member of the International Statistical Institute.
Professor Klein has authored over 50 papers on statistical methodology. His primary research interest is in the area of survival analysis, dependent competing risks theory and methods for dynamic interpretation of time dependent covariates. Dr. Klein is an expert in statistical methods for longitudinal data. He has published extensively on statistical methods for survival data and on the use of these techniques in analyzing complex illness-death models. His areas of research include the use of Stochastic modeling of disease processes.
Other research interest include probabilistic models for cancer and the metastatic process, graphical association models for longitudinal data and techniques for the design and analysis of clinical trials. These techniques have been applied, for example, to transplant data, to data from the Framingham Heart Study and to data from the Danish Breast Cancer Cooperative Group. His research is funded by grants from the National Cancer Institute and NATO. Professor Klein serves as the Statistical Director of the International Bone Marrow Transplant Registry, and as a collaborator on a number of NIH funded projects with investigators at the Medical College of Wisconsin. He serves on the editorial board of Lifetime Data Analysis and IPQAR Transactions.
Recent Publications
Klein JP and Goel P. Survival Analysis: The State of the Art, Kluwer Press, Amsterdam 1992.
Moeschberger ML and Klein JP. “Statistical methods for dependent competing risks.” Lifetime Data Analysis 1:195-204, 1995.
Keiding N, Andersen PK, & John JP (1997). The Role of Frailty Models an Accelerated Failure Time Models in Describing Heterogeneity Due to Omitted Covariates. Statistics in Medicine 16, 215-225.
Andersen PK, Klein JP, Knudsen KM & Palacios R (1997). Estimation of the Variance in a Cox's Regression Model's with Shared Gamma Frailties. Biometrics 53, 1475-1484.
Survival
Analysis: Techniques for Censored and Truncated Data
by Klein and Moeschberger, Springer, 1997
Recent Technical Reports
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- Tech Report #23
- Testing for Center Effects in Multicenter Survival Studies : A Monte Carlo Comparison of Fixed and Random Effects Tests by P. K. Andersen, J. P. Klein and M. Zhang January 1997
- Tech Report #22
- Survival Distributions and their Characteristics, a Contribution to the Encyclopedia of Biostatistics by J. P. Klein December 1996
- Tech Report #21
- Determining when the Survival Rates of Two Treatments are the Same Based on a Censored Data Regression Model by J. P. Klein and M. Zhang December 1996
- Tech Report #18
- A SAS Macro for the Additive Hazards Regression Model by A. Howell and J. P. Klein September 1996
- Tech Report #17
- Analysis of Survival Data : A Comparison of Three Major Statistical Packages (SAS, SPSS, BMDP) by C. J. Pelz and J. P. Klein
- September 1996
- Tech Report #15
- Modeling Multistate Survival Illustrated in Bone Marrow Transplantation
- by J. P. Klein and C. Qian August 1996
- Tech Report #13
- Confidence Regions for the Equality of Two Survival Curves by J. P. Klein and M. Zhang July 1996
- Tech Report #12
- The Role of Frailty Models and Accelerated Failure Time Models in Describing Heterogeneity due to Omitted Covariates by N. Keiding, P. K. Andersen and J. P. Klein January 1996
- Tech Report #10
- Estimation of Variance in Cox's Regression Model with Gamma Frailties
- by P. K. Andersen, J. P. Klein, K. M. Knudsen and R. T. y Palacios
- September 1995
- Tech Report #3
- Statistical Challenges in Comparing Chemotherapy and Bone Marrow Transplantation as a Treatment for Leukemia by J. P. Klein and M. Zhang
- August 1994
- Tech Report #2 ( Click here for Table 5.1 )
- Effects of Model Misspecification in Estimating Covariate Effects in Survival Analysis for Small Sample Sizes by Y. Li, J. P. Klein and M. L. Moeschberger December 1993
- Tech Report #1
- Graphical Models for Panel Studies, Illustrated on Data from the Framingham Heart Study by J. P. Klein, N. Keiding and S. Kreiner
- December 1993
Information on the program DIGRAM